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Ciheb implements projects that further knowledge and improve the treatment of HIV/AIDS and other infectious diseases, such as tuberculosis, hepatitis, and malaria, and supports surveillance systems critical for responding to emerging biosecurity threats. Ciheb is also addressing new challenges presented by the onset of noncommunicable diseases among aging HIV populations. Ciheb emphasizes country ownership in implementing its health system initiatives. Nongovernmental and community-based organizations, universities, and science-based health service providers in multiple African nations today are continuing to carry out programs that originated as Ciheb initiatives.

Below is a brief summary of projects Ciheb is currently implementing. Funding is provided by the Centers for Disease Control under PEPFAR, the World Health Organization, the National Institutes of Health, and by the pharmaceutical industry.


Botswana Partnership for Advanced Clinical Education (CDC/PEPFAR): Focused on improving the quality and scaling up of comprehensive HIV services and supporting HIV in-service training. Supporting more than a hundred Botswana Ministry of Health facilities in 13 districts. Providing preventative interventions in three districts to adolescent girls and young women under USAID’s DREAMS (Determined, Resilient, Empowered, AIDS-free, Mentored and Safe) partnership.

Botswana AIDS Impact Survey (CDC/PEPFAR): A population-based HIV impact assessment assisting the Government of Botswana in measuring progress toward HIV epidemic control. Measuring the burden of HIV in the population and the overall progress (and gaps) in achieving epidemic control.


Boresha Maabara (CDC/PEPFAR): Creating sustainable laboratory quality systems by building the capacity of the National Public Health Laboratory Services, National Blood Transfusion Services, and other relevant bodies of the Ministry of Health. Providing national leadership for and coordination of the provision of sustainable high-quality TB/HIV diagnostic services.

Partnership for Advanced Care and Treatment, Timiza and Endeleza (CDC/PEPFAR): Providing comprehensive HIV prevention and treatment programs in the Western Region and Turkana and Nairobi City Counties.

Technical Assistance for Public Health Impact in Kenya (CDC/PEPFAR):  Providing support for HIV and TB program implementation, laboratory support, and evaluation. Also supporting noncommunicable disease surveillance, management support of the HIV research laboratory, and support for the Health Demographic Surveillance System.

Optimizing Smoking Cessation Interventions for People Living with HIV in Nairobi (NIH): Research aimed at designing and developing an intervention to optimize smoking cessation among medical assisted therapy patients who are HIV-positive. Providing policymakers, community leaders, and clinicians with critical evidence of the most effective smoking cessation treatments for HIV smokers in the methadone maintenance setting.


Accelerating Malawi’s PEPFAR Laboratory Logistics and Infrastructure for Quality (CDC/PEPFAR): Implementing a sustainable laboratory quality system by building the capacity of the national molecular laboratories and district laboratories. Strengthening existing national reference testing and activities, including confirmatory tests for national discordant/indeterminate HIV rapid test results, recency testing, HIV drug resistance testing, results interpretations, continuous quality improvement, site certification, and post market surveillance.


Laboratory Systems Enhancement for AIDS Pandemic Control (CDC/PEPFAR): Implementing a sustainable laboratory quality system to support the National HIV Program by building the capacity of the national molecular laboratories and district laboratories. Supporting the Ministry of Health in strengthening laboratory capacity and improving quality of diagnostic services for HIV viral load, early infant diagnosis, and tuberculosis at all levels of health care in the country.


Strengthening HIV Field Epidemiology, Infectious Diseases Surveillance, and Lab Diagnostics (CDC/PEPFAR): Supporting the PEPFAR Nigeria program to improve the quality of HIV service delivery by instituting a standardized monitoring and evaluation processes in routine data quality assessment and improvement, supporting and strengthening the health management information system, and conducting evaluations.

Nigeria HIV/AIDS Indicator and Impact Survey (CDC/PEPFAR): Implementing the largest population-based HIV survey ever conducted. Preliminary results have been disseminated to the global community.

Strengthening Epidemic Response Systems (CDC/PEPFAR): Establishing a surveillance reporting system in 270 local government authorities across 29 states, strengthening weekly epidemiology reports at the national level, implementing a bio-surveillance information system to improve early threat identification, and enhancing the laboratory information systems of 11 laboratories to strengthen workflow management and quality assurance.


Partnership to Implement Quality Improvement Strategy in the Prevention of Mother-to-Child Transmission of HIV (UNICEF): Training and mentoring healthcare providers to integrate continuous quality improvement strategies at 18 healthcare facilities in the capital city of Kigali to reduce maternal to child transmission of HIV, and improve family testing within ART clinics. Utilizing a Ciheb-developed web-based CQI app for tracking progress and gaps to prioritize technical assistance and to ensure course correction.

Enhancing Sustainable and Integrated Health, Strategic Information and Laboratory Systems for Quality Comprehensive HIV Services through Technical Assistance (Imakaza) (CDC/PEPFAR): Providing technical assistance to the Republic of Rwanda and the Rwanda Biomedical Center’s (RBC) HIV Division by supporting the national reference lab, scaling up of HIV continuous quality improvement and integrated clinical mentorship, conducting an assessment to determine feasibility of an integrated HIV service provision into routine outpatient services, and supporting the RBC to develop HIV guidelines according to PEPFAR priorities.


Reaching, Engaging and Acting for Health Project (CDC/PEPFAR): Supporting the Government of Tanzania, its regional and council health management teams(RCHMT), and local implementing partners in the 10 target regions of Mwanza, Geita, Simiyu, Shinyanga, Mara, Tanga, Dar es Salaam, Pwani, Kagera, and Kigoma in order to optimize RCHMT’s oversight and ownership of HIV services and enhance effectiveness of HIV service delivery.

Afya Kamilifu (CDC/PEPFAR): Providing clinical mentorship services and technical support in differentiated service delivery and quality improvement for health management teams.


Stop Mother And Child HIV Transmission Project (CDC/PEPFAR): Providing comprehensive HIV services by supporting the provision of quality improvement strategies and health system strengthening focusing on 11 districts of Southern Province with 327 selected facilities and health posts.

Zambia Community HIV Epidemic for Key Populations (CDC/PEPFAR): Implementing a comprehensive community-based intervention model that aims at preventing HIV transmission by creating novel systems that ensure each HIV infected person is identified, linked to treatment, and retained in care while HIV-negative clients are linked to prevention services.

Community Impact to Reach Key and Underserved Individuals for Treatment and Support (CDC/PEPFAR): Providing targeted case-finding, linkage to care, prevention, and treatment in Lusaka, Western, and Eastern Provinces for priority populations—including children, pregnant and breastfeeding women, adolescent girls and young women—and key populations—including female sex workers, men who have sex with men, and prisoners.

Zambia Population-based HIV Impact Assessment (CDC/PEPFAR):A nationwide survey assessing the prevalence and incidence of HIV, assessing the coverage and impact of HIV services, and characterizing HIV-related risk behaviors using a nationally representative sample of adults aged 15 years and older. Measuring the burden of HIV in the population and the overall progress (and gaps) in achieving epidemic control in Zambia.



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